Profound
What it means
Meaning 1
Reaching deeply into meaning, understanding, or feeling.
Reach for it when praising insight or emotion whose depth changes how the subject is understood
His question prompted a profound reconsideration of what the archive had omitted.
Meaning 2
Very great in degree or far-reaching in effect.
Reach for it when describing a strong consequential change rather than ordinary importance
The new crossing had a profound effect on access to the clinic.